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It's a real life horror movie: the curse of Ashton Kutcher.

Sure, Kutcher himself continues to thrive in Hollywood.

But over the years, many of his costars have seen their careers suddenly die off.

And those are the lucky ones, as other costars have actually passed away after appearing

alongside the actor.

Here's a look at some of the victims of the the terrifying Ashton Kutcher curse...

Brittany Murphy

Brittany Murphy hit it big with her portrayal of airhead Tai in 1995's Clueless and eventually

became an acclaimed leading actress in hits like 2002's Eight Mile.

"You're gonna be great."

She seemed to have everything, but just a year later it all came crashing down when

she co-starred alongside Kutcher in the disastrous Just Married.

The pair were nominated in the Worst Screen Couple category at the 2004 Golden Raspberry

Awards, with Murphy herself getting a nod with a nominee for Worst Supporting Actress.

A string of critically abused misfires followed, and an attempt to revive her career with voiceover

work was cut short when she died tragically at the age of 32 through a combination of

pneumonia and anemia .

Tara Reid

Tara Reid had a classic starlet's trajectory: first commercials, guest spots in Saved by

the Bell: The New Class and The Big Lebowski, and finally a mainstream smash in the American

Pie films.

Reid's rise ended abruptly when she appeared in one of Kutcher's patented formula rom-coms,

2003's My Boss's Daughter.

Next thing you know, Reid was headlining SyFy channel stinkers and critically reviled bombs

like The Crow: Wicked Prayer and Alone in the Dark.

(screaming while firing a gun at a Sharknado)


Amy Smart

After working her way up with road comedies like Road Trip and Rat Race, Amy Smart co-starred

alongside Owen Wilson and Ben Stiller in 2004's Starsky and Hutch and seemed poised to make

a jump to the big time.

Instead, later that year she became yet another victim of the Kutcher Curse, thanks to her

role in The Butterfly Effect.

While the film generated positive buzz for Kutcher himself, it sent Smart into a career

tailspin she never recovered from.

"What are these?"

"Oh, they're a pair of crotchless panties."

"I know what they are."

Nowadays she's lucky to land supporting roles in critical disasters like Tyler Perry's Single

Mom's Club.

Talk about a butterfly effect!

"Nothing's all better, okay?

Nothing ever gets better!"

Bernie Mac

Two things happened to Bernie Mac in 2005: he starred alongside Ashton Kutcher in Guess

Who, and he announced that he was suffering from the lung disease sarcoidosis.

Despite the presence of both in his life, Mac appeared major box office hits like Transformers

and Ocean's Thirteen.

But in 2008, he sadly passed away from complications related to pneumonia.

Kutcher was one of many former colleagues to show up at Mac's funeral, a huge public

event that was attended by as many as 7,000 mourners.

"He's my mentor.

He's my friend.

And, you know what, I love the guy.

I'll say it."

Lindsay Lohan

Before she was cast as Diane in the 2006 thriller Bobby, Lindsay Lohan actually had a pretty

impressive track record with the critics, starring in the widely acclaimed hits The

Parent Trap, Freaky Friday, and, most famously, Mean Girls, a role that seemed to put the

world at the redhead's feet.

One brush with Ashton Kutcher in Bobby was enough for all of that to come apart.

By 2007, Lohan had been involved in two DUI incidents and a string of high profile meltdowns.

Adding in her many box office flops, and she's become one of Hollywood's most famous cautionary


"When you get bit by a snake, you're supposed to suck the poison out.

That's what I had to do, suck all the poison out of my life."

And that poison's name?

Take a wild guess.

Katherine Heigl

Katherine Heigl is kind of like a female Ashton Kutcher, so when the two teamed up for the

2010 romcom Killers, you knew something had to give.

And that something turned out to be Heigl's career.

"I don't even know who the hell you are."

"It's me!

I just have a different resume."

Already shaky from previous romcom bombs, Killers cemented her reputation as a box office


"It's really, really hard, and I don't know what I'm doing."

Of the next six films she released, five have Rotten Tomatoes scores of 10 percent or less.

How bad has it been?

Heigl eventually resorted to TV commercials for kitty litter.

Now there's a fitting metaphor for the Ashton Kutcher Curse.

"I didn't mean to go poopy in your litter box."

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