The full form of OOF is out of office
“OOF” means “out of office.”

This is phrase is commonly used when talking about where someone is at a certain point throughout the day. It means that the person you are talking to, or want to talk to, is currently unavailable. They are not present, they are “out of (the) office.”

While most cases of “OOF” will mean “out of office,” it can sometimes be read as “oof.” When said as a word and not read out as “O-O-F,” it is a kind of exclamation. It shows surprise, pain, or a general reaction to some type of action or news. This is also used in Spanish speaking countries and is written “uf” but pronounced the same way (like “goof” without saying the “g”).

Conversation Examples
Let’s look at some examples:

Example 1:

Co-worker 1: This quarter was looking good! I can’t wait to see what kind of bonus I’ll get.
Co-worker 2: For sure. I’m looking forward to it too. Do you know when we’ll find out?
Co-worker 1: IDK, Bruce should be able to tell us something soon. Do you know where he is?
Co-worker 2: IDK either. I think he’s OOF today. Maybe he’ll be back tomorrow?
Co-worker 1: Too bad, I guess we’ll have to wait.